AcquaGuard is a project funded by the Italy – Croatia INTERREG Programme aimed at developing the capabilities of local and regional governments to systematically plan, integrate, and implement Nature-Based Solutions (NBS) to face climate-related risks and hazards. In particular, through intensive cross-border cooperation between partners, as well as a co-creation process with all relevant stakeholders, AcquaGuard will offer a comprehensive approach for deploying NBS focused on flood prevention, to regions and cities. The cross-border cooperation will be fully leveraged within the project by developing a Decision Support Matrix for NBS prioritization and selection, capacity-building sessions, project documentation, and other joint dissemination activities.